Microstructure Bioequivalence of Polymer-based Long-acting Drugs

26 September 2022 09:10 - 09:40

The study will determine the relationship between the drug microstructure (including microporosity) and in vitro release characteristics. The effect of manufacturing conditions on the release properties and physicochemical characteristics will also be examined. The project seeks to establish quantitative microstructure imaging analysis as a supplemental modeling tool to current in vitro approaches. Establishing their correlation and use of microstructure imaging may ultimately be a significant asset in developing alternative novel approaches for assessing bioequivalence.

Diane J. Burgess, Ph.D., Board of Trustees Distinguished Professor of Pharmaceutics Pfizer Distinguished Chair of Pharmaceutical Technology , University of Connecticut