Particle Size Control Through Micronization: Challenges and Solutions

27 September 2022 10:15 - 10:45

  • Micronization is an important technique in drug formulation, but not all substances are simple to process.
  • This presentation will give an insight into how micronization processes can be developed for challenging inhalation materials.
  • What technical issues need to be addressed if an API is to be successfully micronized?
  • A robust process development strategy will be presented that ensures all attributes critical for quality are maintained, even for the most challenging.
  • A case study on the micronization of a highly potent inhalation API with a tendency to undergo surface amorphization will also be presented.
  • Key findings, including solid-state characterization and post-micronization conditioning, will be disclosed